Melatonin, once touted as a panacea and lynchpin of the anti-aging pharmacopoeia, went silent for a few years after the mid-1990s hype surrounding it was largely discredited. It still occasionally rears its head in an biogerontological context, however, with recent studies demonstrating beneficial effects of the compound on age-related decline in the brain and skin.

Now, more good news: Melatonin restores impaired contractility in aged guinea pig urinary bladder. It’s especially good news if you happen to be an incontinent guinea pig.