Reviewing the reviews

Here is the next in what will likely be a long series of semi-regular review roundups — links, without extensive further comment, to the reviews I found most intriguing over the past few weeks months (I went on hiatus during the winter holidays). For the previous foray into the secondary literature, see here.

Alzheimer’s:

• Threats to the Mind. Aging, Amyloid, and Hypertension, Iadecola et al.

Apoptosis & cancer:

• The genetics of the p53 pathway, apoptosis and cancer therapy, Vazquez et al.

Calorie restriction:

• Endocrine alterations in response to calorie restriction in humans, Redman & Ravussin

Diabetes:

• Diabetes and the risk of multi-system aging phenotypes: a systematic review and meta-analysis, Lu et al.

Klotho:

• The Klotho gene family, the endocrine fibroblast growth factors, Kurosu and Kuro-o

Sirtuins:

• How does SIRT1 affect metabolism, senescence and cancer?, Brooks & Gu

Stem cells:

• Stem Cells, Their Niches and the Systemic Environment: An Aging Network, Drummond-Barbossa

Telomeres:

• …and progeria: Telomere dysfunction and dyskeratosis congenita, Walne & Dokal
• …and structure: Telomere-associated proteins: cross-talk between telomere maintenance and telomere-lengthening mechanisms, De Boeck et al.

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